PATTERNS OF INFLAMMATION, MICROSTRUCTURAL ALTERATIONS, AND SODIUM ACCUMULATION DEFINE MULTIPLE SCLEROSIS SUBTYPES AFTER 15 YEARS FROM ONSET

Patterns of inflammation, microstructural alterations, and sodium accumulation define multiple sclerosis subtypes after 15 years from onset

IntroductionConventional MRI is routinely used for the characterization of pathological changes in multiple sclerosis (MS), but due to its lack of specificity is unable to provide accurate prognoses, explain disease heterogeneity and reconcile the gap between observed clinical symptoms and radiological evidence.Quantitative MRI provides measures of

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Regulation of RASSF by non-coding RNAs in different cancers: RASSFs as masterminds of their own destiny as tumor suppressors and oncogenes

Ras-association domain family (RASSF) proteins are tumor suppressors and have gained phenomenal limelight because of their mechanistic role in the prevention/inhibition of carcinogenesis and metastasis.Decades of research have demystified wide ranging activities of RASSF molecules in multiple stages Green Coffee Bean Extract of cancers.Although maj

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